Increase In Deaths Linked To First Line Treatment With Sulfonylureas

First-line treatment with sulfonylureas instead of metformin in people with type 2 diabetes is associated with a significantly elevated risk of death, according to results from an observational study presented at the European Association for the Study of Diabetes (EASD) meeting in Barcelona. Although guidelines do not recommend the use of sulfonylureas for first-line treatment, the drugs are…

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Large NIH Trial Finds No Cardiovascular Benefits For Weight Loss And Exercise In Type 2 Diabetics

A large NIH-sponsored trial has found that an intensive lifestyle intervention was no better than standard care in reducing cardiovascular events in people with type 2 diabetes. The results of the Look AHEAD trial were presented today at the American Diabetes Association meeting and published simultaneously in the New England Journal of Medicine. 5,145 people with type 2 diabetes were randomized…

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