Adding more confusion to an already fishy story, a new study has found a significant association between omega-3 fatty acids and the risk of prostate cancer. Although the linkage had been previously observed, the finding surprised the investigators, who wrote that “these findings contradict the expectation that high consumption of long-chain omega-3 fatty acids and low consumption of omega-6 fatty acids would reduce the risk of prostate cancer.”
In a report published in JNCI, investigators analyzed data from men who had participated in the SELECT (Selenium and Vitamin E Cancer Prevention Trial) trial. They compared 834 men who developed prostate cancer with 1,393 matched controls. When compared with men who had the lowest levels of omega-3 fatty acids, men in the highest quartile of omega-3 fatty acids were at significantly increased risk for low-grade, high-grade, and total prostate cancer:
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