A new meta-analysis published in JAMA offers the best evidence yet that the flu vaccine may help prevent cardiovascular events.
Jacob Udell and colleagues analyzed data from 5 published clinical trials in which 6,469 patients were randomized. People who received the flu vaccine had a significantly lower risk of cardiovascular events. The protective effect was largely restricted to people who had had a recent acute coronary syndrome (ACS). Cardiovascular events occurred in 2.9% of people in the vaccination group versus 4.7% of controls (RR 0.64, CI 0.48-0.86, p = .003).
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