Digoxin is one of the oldest drugs in the cardiovascular arsenal, derived from the foxglove plant and first described in the 18th century by William Withering. It is frequently used in patients with heart failure (HF) and with atrial fibrillation (AF). The few trials supporting its use were performed in HF patients before newer treatments arrived. There have been no good trials in AF.
A new observational study published in the Journal of the American College of Cardiology now provides the most detailed perspective on digoxin use in AF. …
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J Am Coll Cardiol. 2014; 64(7): 660-668.
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