Skeptics and the Pandemic

I recently posted the following thread on Twitter: I am so disappointed by the large number of pre-pandemic medical skeptics who have now turned into mask/vaccine skeptics. I largely agreed with many of them back in the day. /1 Pre-pandemic they used their skills and intelligence to rightfully question whether, say, a stent should be inserted…

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Should the ACC Have a Live Meeting?

I was surprised to learn from a recent press release that the American College of Cardiology is planning to have some live participants at its annual scientific sessions meeting in May. The college said it is also partnering with a technology company to offer these participants a wearable monitoring device “as an added safety measure…

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The Defense of Science in the Age of Fake News

Fake news didn’t just become a problem because of Trump, or the pandemic. It’s been around for a long while. The problem can’t begin to be solved unless the medical and scientific community accepts that it has an absolute responsibility to aggressively debunk fake news and defend and support scientific principles. Click here to read…

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Cardiology Research: Business As Usual During the Pandemic

At this moment in time the pre-pandemic cardiology research agenda needs to be completely reprioritized. There are two broad areas that now take precedence over all existing research concerns. On the one hand, researchers need to achieve a better understanding of the staggering incidence of deferred or delayed treatment of cardiovascular events and conditions as…

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The Decline of Science In the Pandemic

Early in the pandemic there was a widespread belief that science would be our salvation. With the help of science we would be spared the worst consequences, such as occurred during the 1918 Spanish flu pandemic. A vaccine would arrive, reliably, after a few hard months of research, and in short order the problem would…

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A COVID-19 Cardiac MRI Study: What Went Wrong?

We still don’t know what COVID-19 is doing to the heart or how we should be investigating it and treating it. Last month JAMA Cardiology published a German cohort study of 100 patients recently recovered from COVID-19… A number of striking problems with the study were noted on Twitter……

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Don’t Confuse the Art and Science of Medicine: PCI vs CABG for Left Main Disease

It is often said that medicine is both an art and a science. In an imperfect world this is both inevitable and desirable. But it is extremely important that the two should not be confused with each other. In particular, because the “science” side of the equation has achieved overwhelming prestige and authority, it is…

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News About CardioBrief and CVCTCardioBrief

Note to readers: After a period of inactivity CardioBrief is coming back, but with some big differences. This website, CardioBrief.Org, will remain my personal website. A new website, CVCTCardiobrief.com, will be the new home for my “professional” blogging activities. To develop this website I have joined forces with the global CVCT Forum. I look forward to…

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No, CRISPR Is Not Going To ‘Cure’ Heart Disease

No, CRISPR gene editing technology is not going to “cure” heart disease. But a New York Times story by Gina Kolata on an extremely early study in animals prominently plays up just this extremely unlikely claim. The Times story is based on a press release issued by Verve Therapeutics, a new biotechnology company founded by Sekar Kathiresan, an influential cardiologist and genomic…

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What Can We Learn From The Apple Heart Study?

Do we ever learn from our past mistakes? For many years we believed that technology was an inevitable force for good. It would give us instant access to a near infinite amount of information and allow us to easily and instantly connect with nearly anyone on earth. What could go wrong? The answer is that…

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Health Hype Alert: Beware the Apple Watch

This morning STAT published an Op-Ed piece I wrote about the Apple Watch. Here’s how it starts: Set your smartwatch alarm. You’re about to be barraged by tons of hype about the health benefits of the Apple Watch. Unfortunately, it won’t include essential information and data that can put these claims in proper perspective. Last year,…

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The Simple Truth About Fake Medical News

Note: This is a slightly revised version of a talk I delivered at the recent CVCT Conference in Washington, DC.  Why are we vulnerable to fake news and why is it so hard to get rid of it? This is a complex question, but one important factor is that fake news delivers clear and simple…

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Questions Raised About Invokana Label Expansion For CV Risk Reduction

It hasn’t received a lot of media attention but on Tuesday the FDA approved an expansion of the canagliflozin (Invokana, Janssen) label to include a reduction in the risk of heart attack, stroke, or CV death in adults with type 2 diabetes and established CV disease. Canagliflozin, an oral SGLT2 inhibitor, thus becomes the third…

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Cardiovascular Research Foundation Blocks Press Access to TCT2018 Meeting

(Updated) The Cardiovascular Research Foundation (CRF) has denied press credentials for the TCT2018 meeting to a legitimate, fully accredited journalist. The meeting, which starts this weekend in San Diego, is the premiere interventional cardiology meeting. Legitimate journalists are routinely granted access to cover medical and scientific meetings. By any standard, Cat Ferguson is a respected and…

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Right Wing Minority Rule

The US is not perfect but until recently it has always moved, inexorably, if slowly and fitfully, in the general direction of justice and greatness. The best and undeniable example of this in recent times is the election of Barack Obama, something which would have been unthinkable at any other time in our history. But…

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What Happens When A Healthy 86-Year-Old Gets Atrial Fibrillation

Editor’s note: 86-year-old Nina Mishkin was still healthy and active when she went to Dublin, Ireland last September. After she returned home she developed atrial fibrillation, and then much more. “I never felt particularly vulnerable and fragile before,” she writes. “Now I do… It’s a different universe I inhabit.” I am grateful to Nina for giving…

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Lancet Paper Adds To Evidence That Reducing Salt To Very Low Levels May Be Dangerous

A new paper from a very large ongoing observational study offers additional and more powerful evidence that dramatic reductions in salt consumption may not be beneficial and might even prove harmful. The finding supports growing criticism that current guideline recommendations to dramatically lower salt intake in the general population may be misguided. The study also…

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No, A Big NIH Trial Did Not Show That Lowering Blood Pressure Will Prevent Dementia

It’s “breakthrough” time again. News reports out of the Alzheimer’s Association International Conference (AAIC) this week have been relentlessly upbeat and positive about findings from the NIH’s SPRINT MIND study. The message: aggressive blood pressure control can help protect the brain. But unless you look very carefully at the news reports and “expert” statements you won’t…

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Warning: Pirate Sites Are Now Kidnapping Doctors Booking Hotels At Medical Meetings

Pirates are attacking interventional cardiology meetings. Interventional cardiologists planning to attend the upcoming TCT meeting should be aware that at least one pirate web site is out to dupe them. (The annual TCT meeting, which runs this year in San Diego from September 21-25, is the première meeting for interventional cardiologists.) The pirates are trying…

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If You Look For Atrial Fibrillation You Will Find Atrial Fibrillation

If you look hard to find people who have atrial fibrillation (AF) you will in fact find people who have atrial fibrillation, a new paper published in JAMA shows. But the paper offers no evidence whatsoever that the new diagnosis improves outcomes in these people, though it does find that the diagnosis leads to increased use of…

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1 in 4 Cardiovascular Patients in Low Income Families Have Significant Financial Pain

Editor’s note: The following guest post is by Khurram Nassir, a cardiologist at the Yale University School of Medicine. He is the senior author of a new paper in JAMA Cardiology, “Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States.” 1 in 4 Cardiovascular…

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On Cannibals And Cardiologists

Everyone knows that cannibalism was practiced widely in pre-Colombian Mexico. Go online and you will quickly learn that 15,000 to 20,000 Aztecs were sacrificed each year. This “fact” colors our view of that civilization, and makes it a bit easier to give a pass to the conquistadors who, for all their own rapacity, brought “civilization”…

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Outsiders Swoop In Vowing To Rescue Rural Hospitals Short On Hope — And Money

Editor’s note: the following article is reprinted with permission from Kaiser Health News. Links to previous CardioBrief coverage of the laboratory scandal story can be found at the bottom of the page. by Barbara Feder Ostrov, Kaiser Health News CEDARVILLE, Calif. — Beau Gertz faced a crowd of worried locals at this town’s senior center,…

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New ORBITA Findings May Offer Modest Symptomatic Pain Relief To Interventional Cardiologists

New data presented at EuroPCR from the much debated ORBITA trial may provide some modest temporary lessening of the pain felt by interventional cardiologists in response to the initial negative ORBITA findings. But the pain relief is likely to be only temporary, and might even be fairly compared to a placebo effect, since the major…

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NIH Halts Large Cardiovascular Inflammation Reduction (CIRT) Trial

The NHLBI has put an early stop to the large Cardiovascular Inflammation Reduction (CIRT) Trial. The NHLBI action was based on a recommendation from the trial’s Data and Safety Monitoring Board. The action was not based on any substantive safety concerns. “Sometime in late March or early April the NHLBI informed me that there were no substantive…

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