Although current guidelines recommend that ACE inhibitors and angiotensin-receptor blockers (ARBs) be used in high doses in patients with congestive heart failure, many CHF patients currently receive lower than recommended doses of these drugs. In a research letter published online in Archives of Internal Medicine, investigators in Montreal analyzed data from 43,405 patients with a first…
Many CHF Patients Not Receiving– Or Getting Benefits From– High Dose ACE Inhibitors And ARBs
July 3, 2012 by Leave a Comment
Olmesartan Use Associated With GI Disorder That Mimics Celiac Disease
June 21, 2012 by Leave a Comment
A gastroenterologist at the Mayo Clinic has uncovered a rare but potentially serious association between the angiotensin II receptor antagonist (ARB) olmesartan and severe gastrointestinal problems that resemble Celiac disease. The report has been published online in Mayo Clinic Proceedings. In the US, olmesartan is sold as Benicar and, in combination with other drugs, as…
Study Evaluates Losartan Efficacy in Heart Failure
April 11, 2012 by Leave a Comment
The angiotensin II-receptor blocker (ARB) losartan has labored under the perception that it is not as potent as other ARBs, and some evidence has suggested that it may not confer the same clinical benefits as other ARBs in heart failure patients. In a paper from Denmark published in JAMA, Henrik Svanström and colleagues performed a country-wide registry study…
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