A Guide To The Raging Debate Over The NIH’s TACT Chelation Trial

(Updated) The publication in JAMA of the NIH’s Trial To Assess Chelation Therapy (TACT) trial has provoked a fascinating debate in the blogosphere. The vast majority of responsible physicians and healthcare professionals have little interest in chelation therapy per se, but the TACT trial has raised many important questions about the nature of medical evidence. Here’s a brief…

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‘Bias in choosing the question is a much bigger issue than lying about the data’

Robert Califf takes questions about conflict of interest from Harlan Krumholz. Here are a few choice quotes. Read the entire Q&A on CardioExchange. …focusing exclusively on the medical products industry and failing to consider other sources of conflict of interest is a huge mistake and leads to sensationalism that then engenders reactive rules that add to bureaucracy…

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Missing Data: The Elephant That’s Not in the Room (Guest Post)

Editor’s Note: The following guest post by Harlan Krumholz is reprinted with permission from CardioExchange, the cardiology social media website published by the New England Journal of Medicine. Missing Data: The Elephant That’s Not in the Room by Harlan M. Krumholz, MD, SM There is a problem so grave that it threatens the very validity of what we…

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