Large Meta-Analysis Quantifies Risk Of NSAIDs And Coxibs

Findings from a very large meta-analysis of clinical trials of NSAIDs may now allow physicians to quantify the cardiovascular and gastrointestinal risks associated with these drugs. The results of the Coxib and traditional NSAID Trialists’ (CNT) Collaboration, employing data from more than 350,000 randomized patients, have now been published in the Lancet. Here are some of the key findings:…

Click here to continue reading…

Acute Kidney Injury Associated With Dual Antihypertensive Therapy And NSAIDs

Adding a non-steroidal anti-inflammatory drug (NSAID) to dual antihypertensive therapy (a diuretic plus either an ACE inhibitor or an angiotensin receptor blocker) is associated with an increase in risk for kidney injury, according to a large new retrospective study published in BMJ. Click here to read the complete story on Forbes.  …

Click here to continue reading…