More Mini-Trials And Fewer Mega-Trials?

Just as dinosaurs ruled the earth for millions of years, for more than 30 years now cardiology has been ruled by mega-trials. Over the years the cardiology landscape would shake and tremble as ever more gigantic mega-trials emerged to  dominate the field. Just as the giant dinosaurs paid no attention to the seemingly inconsequential little…

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Side Effects In Drug Ads Don’t Add Up

–The long recitation of all possible side effects dilutes the perception of risk. One of the most perplexing aspects of the ubiquitous direct to consumer (DTC) prescription drug advertisements is the seemingly endless recitation of side effects in drug ads. The list is, alternatively, horrifying, boring, concerning, and silly. It is reasonable to wonder how these…

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Rigorous Study Debunks Alarms That Statins Cause Muscle Problems

(Updated, May 2, May 4) –The authors say muscle problems with statins are an example of the ‘nocebo’ effect. A new study helps debunk the widespread belief that statins cause muscle-related pain and weakness in large numbers of patients. The “nocebo effect” may be the cause of the epidemic of muscle pain among statin users,…

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